Research programmes supported are part of New Ideas scheme

The Little Princess Trust is proud to announce the funding of five pioneering research projects through our New Ideas grant scheme.

This scheme supports early-stage, innovative ideas that have the potential to transform the treatment and care of young people with cancer.

This stage is critical for research, and researchers desperately need support to explore their ideas – and potentially make progress towards the next big breakthrough.

Phil Brace, from The Little Princess Trust, said: “We are proud to offer funding for researchers at the earliest stages of their research.

"This funding gives researchers the chance to explore bold new ideas – like the Prof Rylie Green, who is developing a new way of treating childhood brain tumours, or Prof John Anderson, who is creating advanced immunotherapies that can ‘rest and recover’ while fighting cancer.

“Through initiatives like the New Ideas scheme, we are ensuring that our amazing supporters will have the biggest impact in shaping a brighter future for children with cancer.”

The 2025 New Ideas projects will explore:

• A new approach to deliver chemotherapy directly into brain tumours – Prof Rylie Green.

• Finding kinder drugs in genetically matched cell models for childhood leukaemia – Dr Alex Thompson.

• Developing a new drug for the treatment of ALT-positive cancers – Dr Jon Elkins.

• Making CAR-T cells that can rest to improve their cancer-fighting ability – Prof John Anderson.

• Fighting brain cancer with CAR-T cells: Targeting zombie cells to improve therapy - Dr Ashley Vardon.